Scientist Assay Development at Pivot Park Screening Centre (PPSC)
Pivot Park Screening Centre (PPSC) is a quickly growing company in drug discovery research with a main focus on ultra-high throughput screening. Using our state-of-the-art robotic systems we work together with customers ranging from big pharma companies to small & medium biotech companies and universities. We offer services in early drug discovery in the field of assay development, compound screening and biological profiling during hit to lead phase. PPSC is also actively involved in the European Lead Factory (ELF; IMI initiative) as the beating heart of the European Screening Centre. Besides strengthening the PPSC core business we are also expanding in areas like Hit-to-Lead profiling and precision medicine. To expand our capacity, we are looking for an enthusiastic and motivated bachelor level scientist.

Job Description
You and your colleagues from the assay development team are responsible for setting up, optimizing, miniaturizing and transferring assays to the automated screening facilities. The actual screening is performed in close collaboration with lab automation experts who have the in-depth knowledge and ownership over the lab automation infrastructure. Assays are set up to identify compounds giving a positive response (actives) against the assay targets. These assays are provided by external partners like pharmaceutical companies, universities and SME’s. The scientist assay development is involved in a variety of tasks: the handover of assays from the target owner/customer, optimization of the assay, actual screening, active selection and retesting (active confirmation), data processing and reporting. The scientist assay development is participating in international programme teams (target owners and ELF partners).

Our job requirements:
• Bachelor or Master degree in biochemistry, chemistry, biology or life sciences;
• Experience with assay development, biochemical and cell based assays;
• Affinity for lab automation and knowledge of general IT;
• Good communication skills, in Dutch and English and willing to collaborate with colleagues and customers.
Your competencies:
• Team player;
• Accurate;
• Eye for details;
• Commercial mind-set;
• Good social skills;
• Responsible.

Plusses when you have experience with:
• Analytical chemistry;
• Cell culture;
• Assay development for 384- and/or 1536-wells assay technologies;
• Laboratory automation and HTS (High Throughput Screening) using robotic systems;
• Various assay technologies such as: fluorescence polarization, luciferase, alpha screen, beta-lactamase, fluorescence resonance energy transfer, LC-MS, SPR, MST, flow cytometry, HCA.

Job application an information:
If you are interested in this position and you would like to apply or you would like to have more information, please contact Hanny Faro (HR Business Partner), by telephone: +31 629037162 or via e-mail: hanny.faro@pivotpark.com

Applications* must include all of the following:
– a personal motivation letter.
– a Curriculum Vitae including the names and contact details of some references.

*Only complete applications will be considered. Screening of applicants will start as soon as applications are received and will continue until the position has been filled.

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