Looking for space?
Login
Search
Close this search box.

Senior Research Scientist

Are you passionate about shaping the future of drug discovery?

Senior Research Scientist BioScience (PhD + Postdoc experience)

Oss, The Netherlands
Fulltime

In our BioScience team at Acerta Pharma (European R&D centre of AstraZeneca in Oss) we have a position available for a strong, motivated, and creative Senior Research Scientist with a proven track record in (hemato)-oncology.  In this lab-based position, you will be part of our BioScience team and have a significant contribution to the forefront of hematologic cancer biology from target discovery through drug candidate selection.

Why us?
Cutting edge projects: you will be working on the identification of drug targets and next generation drugs that have the potential to improve the quality of the patients’ lives.

Multidisciplinary collaboration: you will collaborate with experts within Acerta Pharma and AstraZeneca from diverse fields (such as molecular biology, computational chemistry, drug safety sciences), fostering a dynamic environment.

Innovation culture: we stimulate our innovation culture: your ideas are not just valued, but actively encouraged. Your voice matters at Acerta Pharma.  

With your deep knowledge of new target validation and compound screening / profiling strategies you will be working in our new state of the art laboratory together with your colleagues of the BioScience and chemistry departments.

Your challenge:

As a Senior Research Scientist, you are an expert within the BioScience team of Acerta Pharma in new drug target validation and biochemical & cell-based assay development and applications. You will design, perform, and interpret experimental data from various sources.  In cooperation with medicinal chemists and the Biochemical and Cellular Support Team, you will identify, validate, and design profiling cascades aimed at the development of new drug candidates as future treatment of hematological tumors.


What will you be doing?

  • You will take responsibility for the design, execution, and interpretation of biological studies as starting points for the development of future compound profiling assays.
  • You will be responsible for the design, validation, implementation, and interpretation of data from biochemical and cell-based assays for the profiling of small molecule inhibitors.
  • You will support project leaders in the validation of newly synthesized compounds and the design of relevant assays.
  • You will actively collaborate with fellow scientists from other departments of AstraZeneca in Cambridge (UK), Boston, Gaithersburg and South San Francisco (US).
  • Your entrepreneurial attitude will help to achieve Acerta Pharma’s research goal to implement novel findings and compounds into clinical practice.
  • You are responsible for accurate and well-organised laboratory records, worksheets and notebooks.


What do we ask of you?

  • You have completed a PhD in Biology, Biochemistry or Biomedical Sciences, plus a minimum of 5 years postdoctoral experience, with a strong insight in (hemato)-oncology mechanisms on the biochemistry and molecular biology level that can be implemented in future research strategies.
  • A background in the pharma industry is preferred.
  • Experience with target identification and validation, biochemical and cell-based assay development and drug target validation is a must.
  • In the hit-identification and lead-optimisation process for the selection of candidate medicines for future clinical application you have experience with various biochemical assays as well as cellular screening techniques including flow-based cytotoxicity assays.
  • Track record of successful development and implementation of strategies and initiatives in (hemato)-oncologic research.
  • Excellent project management skills, including prioritisation, time management and progressing research projects.
  • Solid understanding of the drug discovery process with a major focus on small molecule research and able to work in a matrix organisation.
  • Proficient in analysing complex data sets resulting from diverse research disciplines relevant to internal projects.
  • Scientific expert in the field with a strong publication track-record.
  • Excellent and strong communicator.

We will only consider candidates who are already living in Europe, and are happy to relocate within easy commuting distance to our offices in Oss, The Netherlands.

What we offer
A dynamic, innovative and international working environment. You are part of the development process of new drugs that can make a difference in the lives of cancer patients and their loved ones. In addition:
•    The opportunity to further develop yourself, for example, into a position offering even more responsibility. International growth (within AstraZeneca) is also one of the possibilities.
•    Good primary & secondary benefits including 8% holiday allowance, 25 holidays on a full-time basis plus office closure between X-mas and New Year + Good Friday. 
•    Collective pension with a fixed percentage personal contribution.
•    Bonus scheme. 
•    Personal budget which can be used for vitality, home office equipment, sustainability or personal development. 
•    Access to internal training and learning and development offerings. 

For expat candidates we offer
•    a relocation package (including support for the application to the tax authorities for the 30% tax ruling).
•    an expat program, including a Dutch language course and the opportunity to learn more about the Dutch culture.

Acerta Pharma 
At our international headquarters in Oss, the Netherlands, we are working to develop new treatment options for patients with specific types of blood cancer. Together with our colleagues of AstraZeneca in US, Canada and UK we are committed to innovative drug discovery and development, especially in the field of hematological oncology.

Acerta has received approval from both the US (FDA) and the European Regulator (EMA) for its small molecule BTK inhibitor for treatment of patients with chronic lymphocytic leukaemia (CLL). In addition, AstraZeneca and Acerta Pharma are collaborating on a large number of other innovative medicines to treat hematological malignant diseases.


Apply:
If you have any questions about this vacancy, our Recruitment Team, Karin Raadschelders / Caroline van Oppen are happy to inform you.  info@werkenbijacertapharma.nl or by phone on +31(0)85 – 047 0244.

Apply by clicking here.

 

Find more careers here.

< Back to careers

Company:

Other vacancies

Looking for
space to grow?

More information
Join us at Pivot Park

Learn about
our companies?

Send us a message
Contact us at Pivot Park

or call

+31 (0)412 84 60 10

Linkedin-in Youtube
Address

Pivot Park – Building RK
Kloosterstraat 9
5349 AB Oss
The Netherlands
+31 (0)412 – 84 60 10
info@pivotpark.com

Post address

Pivot Park  Exploitatie B.V. 
Building OP
Kloosterstraat 9
5349 AB Oss
The Netherlands

Disclaimer  |  Privacy Statement  |  Cookie Statement  |  Purchase conditions

Pivot Park Captains' Dinner

10 years ago, Pivot Park opened its doors to the world. Thanks to your commitment, support and confidence, we have been able to grow it into the successful and innovative biopharmaceutical campus it is today.

Now it’s time to celebrate!

We are therefore delighted to invite you – along with all your fellow CEOs at Pivot Park – to a special night out featuring inspiring art, a wonderful dinner and lots of opportunities to network and exchange ideas.

Erwin Wurm | Am I a House?

For the first time, the artist shows a cross-section of his work, from Narrow Furniture to One Minute Sculptures, within the walls of a historic building. Villa Constance, a former home that today houses Museum Jan Cunen, is not only a location but also part of the conversation. Because what exactly is a house?
Read more (NL)

#100YEARSPHARMAFUTURE

The development of medicines in Oss began one hundred years ago. It was then that the foundations were laid for what would become a flourishing pharmaceutical sector in the Netherlands, leading to groundbreaking discoveries such as insulin and the anti-conception pill.

Today, the entire chain is still represented in Oss, from early-stage research to the commercial scale production of medicines. Working in Oss, we focus on the health of people all over the world. Employees at dozens of companies large and small put their heart and soul into new medicines, products and services that will improve lives worldwide. Together, our strength lies in our combination of broad knowledge about the development of medicines and a thorough understanding of the requirements of high-quality production.

This shared past and common values stimulate strong bonds among everyone who works in pharmaceuticals in Oss. We build on qualities, expertise and networks that go back decades. And with a wide variety of pharmaceutical companies, suppliers and scientific institutions all located nearby, we offer an attractive business climate and an excellent basis for international collaboration.

We are proud to work together to create a better and healthier future for all, a collaboration that in turn fuels growing employment: today, most pharmaceutical jobs in the Netherlands are in Oss. Here we connect talent and companies and stimulate entrepreneurship, while our expert employees are our most important asset. Their drive ensures that Oss has an influence on health all over the world.

Pharma in Oss offers endless opportunities to startups and talent in a city and region that is a joy to live and work in. We are committed to collaboration and sustainable and successful entrepreneurship. Oss’s pharmaceutical companies are intrinsically competitive while also being committed to quality and safety. This, plus their focus on new health solutions and contemporary technology, makes us a leader in our pursuit of a better life for people worldwide.