Pivot Park meets Brainport Eindhoven – ICMS

Technology development for (bio)medical applications

Summary
An important research area at TU/e, and particularly in ICMS, concerns the development of technology for (bio)medical applications. This presentation will focus on the development of micro-physiological models, also known as “Organ-on-Chip” (OoC). For this, we design and realize microfluidic devices as advanced cell culture systems in which in-vitro models of human tissues and organs can be realized, making use of the possibility offered by microfluidics to control the cellular microenvironment (mechanical, biochemical, electrical, etc.). Our recent examples of vesselon- chip, heart-on-chip, brain-on-chip, and cancer-on-chip will be highlighted.

This research has generated knowledge and insights relevant to tissue engineering strategies, development of therapies, and diagnostics. But we are also involved in the development of next-generation of Organ-on-Chip, which is now needed to bring the technology to maturation and to realize implementation in practice, in particular for drug development. Here, manufacturability, scale-up, throughput, ease-of-use, and compatibility with existing workflows, are all key goals.

Collaboration is key in the development of these platforms. In the Brabant ecosystem, collaboration between the complementary parties Pivot Park, Holst Center, and ICMS, would provide a great opportunity. Join Jaap and the ICMS team to discuss the possibilities for collaboration in this exciting area of research.

About the presenter
Jaap den Toonder is full professor and Chair of the Microsystems research section at Eindhoven University of Technology, which he las lead since 2013. Here, about 50 scientists develop innovative technological concepts and fabrication methods for microsystems for a wide range of applications. The concepts are often inspired by biology, and the microsystems are often applied to understand biological processes that are important for health and disease. His current main research interests are: microfluidics, out-of-cleanroom micro-fabrication technologies, natureinspired micro-actuators, soft microrobotics, mechanical properties of biological cells and tissues, and organ-on-chip.

Jaap den Toonder has (co-)authored more than 120 scientific papers, as well as over 40 patent applications, and he has given over 50 invited lectures at conferences. He is the recipient of an ERC Advanced Grant (2019). He is currently leading the Dutch research program “SMART Organ-on-Chip”, in which 10 university groups and 25 companies and institutes participate.

About ICMS
The Institute for complex Molecular Systems at TU/e is home to a vibrant multidisciplinary community of researchers who work to push boundaries in the science of complex molecular systems, which is a major driving force for innovation as it promises the bottom-up design of new functional systems with tailored properties. Our strong internal network, alliances with industry and other (research) institutes across the world, and our facilities and stateof-the-art labs enable us to tackle the greatest challenges in Advanced materials and Engineering Health. To find out more, visit www.tue.nl/icms. Get in touch at icms@tue.nl.

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Hourly Schedule

Programme

15:00
Presentations
Speakers:
Jaap den Toonder
16:00
Q&A
16:15
Coffee & discussions
Jaap den Toonder
Jaap den Toonder
Professor and Chair of the Microsystems research section at TU/e
Jaap den Toonder is full professor and Chair of the Microsystems research section at Eindhoven University of Technology, which he las lead since 2013. Here, about 50 scientists develop innovative technological concepts and fabrication methods for microsystems for a wide range of applications. The concepts are often inspired by biology, and the microsystems are often applied to understand biological processes that are important for health and disease. His current main research interests are: microfluidics, out-of-cleanroom micro-fabrication technologies, natureinspired micro-actuators, soft microrobotics, mechanical properties of biological cells and tissues, and organ-on-chip. Jaap den Toonder has (co-)authored more than 120 scientific papers, as well as over 40 patent applications, and he has given over 50 invited lectures at conferences. He is the recipient of an ERC Advanced Grant (2019). He is currently leading the Dutch research program “SMART Organ-on-Chip”, in which 10 university groups and 25 companies and institutes participate.

Date

Feb 16 2022

Time

03:00 - 05:00

Location

Panorama Room

Organizer

ICMS
Email
icms@tue.nl
Website
http://www.tue.nl/icms
Registration closed

Speaker

  • Jaap den Toonder
    Jaap den Toonder
    Professor and Chair of the Microsystems research section at TU/e

    Jaap den Toonder is full professor and Chair of the Microsystems research section at Eindhoven University of Technology, which he las lead since 2013. Here, about 50 scientists develop innovative technological concepts and fabrication methods for microsystems for a wide range of applications. The concepts are often inspired by biology, and the microsystems are often applied to understand biological processes that are important for health and disease. His current main research interests are: microfluidics, out-of-cleanroom micro-fabrication technologies, natureinspired micro-actuators, soft microrobotics, mechanical properties of biological cells and tissues, and organ-on-chip.

    Jaap den Toonder has (co-)authored more than 120 scientific papers, as well as over 40 patent applications, and he has given over 50 invited lectures at conferences. He is the recipient of an ERC Advanced Grant (2019). He is currently leading the Dutch research program “SMART Organ-on-Chip”, in which 10 university groups and 25 companies and institutes participate.

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