Director Transgenic Platform Support

Pharming is a global, commercial stage biopharmaceutical company developing innovative protein replacement therapies and precision medicines for the treatment of rare diseases and unmet medical needs. The company is poised for further scientific, technological and new product development and additional commercial roll-outs. The company is based internationally and growing quickly. As a result of this growth, we are looking for a Director Transgenic Platform Support

About the role:
The Director Transgenic Platform Support leads and supervises animal scientists, contributing to the optimal health and welfare of all animals within Pharming. The scope of the function covers the biosecurity of the (SPF) colonies/herds, the breeding, male and female reproduction and zootechnical aspects like housing and feeding. In this respect the Director Transgenic Platform Support sets specifications for animals and animal related products, maintains semen and embryo banks and sign off health certificates on the basis of the microbiological status of the colonies/herds.

The Director Transgenic Platform Support creates and maintains a network of (academical) experts who can be consulted for training purposes or additional scientific support.

The Director Transgenic Platform Support chairs the Animal Welfare Body (IvD and supervises the compliance with the Dutch Act on animal experimentation (Wod)

Areas of responsibilities:

  • Animal health and welfare: Set up and monitor a bio security program; control and maintenance of animal health (SPF) status. Prepare and take care of the execution of health management programs. Ensure timely reviews of health screening reports and signing off of health certificates. Take steps in case of health deviations and supervise/verify corrective actions. Write recommendations in case of loss of SPF status and ensures implementation of approved actions. Review and approve facility specifications pertaining to the biosecurity principles of new animal facilities. Supervises animal welfare and act as attending veterinarian according to art. 14 Wod
  • Animal products: optimize specifications for animals, germ cells, feed, veterinary drugs and instruments. During commercial production.
  • Animal reproduction: control and monitor the stability, quality and availability of semen (MTB and MWTB) and embryo’s to ensure the continuation of the animal platforms. Optimize and monitor breeding strategies, provide recommendations on new transgenic lines and the development of new (SPF) colonies or herds
  • Personnel: identify the (scientific) requirements and define roles of employees, select candidates and ensure adequate onboarding education and (continuous) training, organize work force and lead and supervise the team(s) taking into account the career development.
  • Basic Quality System: initiate, review and authorize SOPs, Work Instructions, test protocols and – reports related to animal aspects of the rabbit and cattle platform. Ensure timely preparation of change requests, deviations and CAPA’s and ensure these are managed according to defined timelines. Ensure readiness for inspections by authorities
  • Dossier: Upon request edit relevant parts of the regulatory dossier and formulate answers to regulatory questions
  • Compliance: ensure animals are housed and treated according to relevant (inter)national legislation (EU directive 2010/63, Wod, GMO) and guidelines (e.g. FELASA). Chairs the IvD, nominate members and control proper documentation (e.g. minutes). Manage project applications and changes. Submit yearly registration reports to the NVWA.

Required skills and qualifications in order to be successful in this role:

  • Leadership
  • Vision
  • Communication
  • Decisiveness
  • Problem Analysis
  • Quality orientation

Knowledge:

  • University degree in animal (veterinary) science or equivalent
  • Strong understanding of biosecurity and principles
  • Good command of written and spoken Dutch and  English
  • Adequate knowledge of (inter)national legislation and guidelines with respect to laboratory animals
  • Good grasp of principles of colony and herd health and milk production management
  • Understanding of GMP principles
  • Article 9 WOD certification, including species specific ruminant and rabbit modules


Experience:

  • Minimum of 3 years experience in laboratory animal science
  • Minimum of 5 years of experience in managing (multidisciplinary) teams within scientific ( pharma ) industry

Do you have questions?
For questions please contact Anita Kok, Talent Acquisition Officer by email: a.kok@pharming.com
Do you want to apply? Click the link

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The development of medicines in Oss began one hundred years ago. It was then that the foundations were laid for what would become a flourishing pharmaceutical sector in the Netherlands, leading to groundbreaking discoveries such as insulin and the anti-conception pill.

Today, the entire chain is still represented in Oss, from early-stage research to the commercial scale production of medicines. Working in Oss, we focus on the health of people all over the world. Employees at dozens of companies large and small put their heart and soul into new medicines, products and services that will improve lives worldwide. Together, our strength lies in our combination of broad knowledge about the development of medicines and a thorough understanding of the requirements of high-quality production.

This shared past and common values stimulate strong bonds among everyone who works in pharmaceuticals in Oss. We build on qualities, expertise and networks that go back decades. And with a wide variety of pharmaceutical companies, suppliers and scientific institutions all located nearby, we offer an attractive business climate and an excellent basis for international collaboration.

We are proud to work together to create a better and healthier future for all, a collaboration that in turn fuels growing employment: today, most pharmaceutical jobs in the Netherlands are in Oss. Here we connect talent and companies and stimulate entrepreneurship, while our expert employees are our most important asset. Their drive ensures that Oss has an influence on health all over the world.

Pharma in Oss offers endless opportunities to startups and talent in a city and region that is a joy to live and work in. We are committed to collaboration and sustainable and successful entrepreneurship. Oss’s pharmaceutical companies are intrinsically competitive while also being committed to quality and safety. This, plus their focus on new health solutions and contemporary technology, makes us a leader in our pursuit of a better life for people worldwide.