3D-PharmXchange is a Dutch consultancy firm dedicated to the development of pharmaceuticals and diagnostics. Our goal is to speed up development programmes. To do so, we provide direct solutions that fit your time, cost and risk requirements. Through our long-standing experience, we know how to take your development programme to the next level and to do so seamlessly, including in complex multidisciplinary projects and in a wide range of disease areas. We have expertise in CM&C (formulation development), clinical development (including programming and modelling), non-clinical development (including toxicology), regulatory matters and project and line management. In addition to our own expertise, we also have an extensive network in the life sciences industry.

Acerta Pharma is a leader in the field of covalent binding technology and is applying this technology to create novel, highly selective therapies for cancer. In February 2016, AstraZeneca acquired a majority share of Acerta Pharma via a USD $4 billion investment. The company is a committed partner in the development of these innovative drug candidates.

Agidens helps its customers to improve processes through specialty advice, engineering, automation solutions and maintenance services.

Ardena Oss supports pharmaceutical companies worldwide with the development of their innovative products. Ardena Oss has expertise in Active Pharmaceutical Ingredients and nanomedicines. For these innovative products, Ardena Oss develops and validates the manufacturing process and the analytical methods, and performs the cGMP manufacture, quality control and stability studies.

Arnold & Siedsma is a specialist in the legal protection of intellectual property rights with over 100 years of experience. Arnold & Siedsma  employs over 140 employees, including more than 45 attorneys at law, patent attorneys (Dutch, Belgian and European) and trademark attorneys.

Our services vary from assessing innovations, formulating and obtaining patent and trademark requests, protecting patent and trademark rights in case of transgression to providing strategic and operational IP advice. This allows you to focus all your energy on turning your idea or invention into a commercial success.

We make the restaurant a beating heart of the organisation. As a family business, we fulfill your wishes with attention and passion. Connecting together, enjoying together, and growing together; is our focus.

BG.legal is a full service law firm with 20 lawyers. Life Sciences & Pharma is one of the sectors we focus on. We advise clients on issues like IP, contracts, privacy, competition issues, pharmaceutical law, the advertising of medicines, nutrition and health claims, M&A and more.

BioAxis Research provides computational medicinal chemistry, cheminformatics and structure-based drug design services. Using our expertise in state-of-the-art in silico tools, and our strong background in the pharmaceutical industry, we work with clients ranging from academic spin-offs, small-scale start-ups through to big pharma. We work in secure, professional collaborative research projects, helping our clients to identify leads, follow up on early stage discovery activities and develop drug candidates.

BioConnection B.V. was founded more than 10 years ago, since when we have built a strong reputation for contract services and GMP manufacturing for the development and production of sterile biopharmaceutical drug products. We operate from our state-of-the-art facility in Oss, which has EMA and FDA certification and is ideally suited for small to medium batch sizes for both clinical trial material and commercial product supply. Our own key CMC services are: Drug Product Development, Fill & Finish, Freeze-drying and a broad range of Drug Product supporting services. BioConnection’s clients are biotech and pharma companies worldwide. We bring value to our customers through our expertise, dedication, customer orientation and flexibility.

Cell4Pharma is a commercial joint-venture company between Ekoy Investment Partners and the Stichting Radboud UMC (Radboudumc), in the Netherlands. 

The company is backed by high-levels of business experience in pharma and biotech through Ekoy’s leadership team and high levels of scientific expertise in renal toxicology and physiology, through close direct relations with the Departments of Pharmacology and Toxicology and Pediatrics of Radboud UMC. In addition C4P is already backed by sales-revenues from renowned and top 10 global pharmaceutical companies and medical faculties of top universities globally.

Certara, and its Dutch affiliate Quantitative Solutions, provides pharmacometric services in support of drug discovery and development. The core of our services lies in the development of mathematical-statistical models that enable the analysis and interpretation of data from (pre-)clinical studies. Simulations from these models help to inform a wide variety of decisions during R&D and as part of regulatory review and approval.

Citryll is taking a new approach to treat autoimmune and other human diseases, such as lupus, vasculitis, pulmonary fibrosis, rheumatoid arthritis and organ damage due to sepsis. This approach involves targeting and inhibiting the source of auto-antigens and neutrophil extracellular trap (NET) derived toxic molecules, rather than broadly targeting inflammation or acquired immunity. The latter are the MoAs of current medicines like anti-TNF antibodies, small molecule Jak inhibitors and antagonists of B cell biology like anti-CD20 antibodies. Citryll’s lead programme targets the formation of neutrophil extracellular traps, called NETs and its pathological consequences. Citryll BV is a private pharmaceutical company that is dedicated to the development and commercialisation of therapeutics that target NETosis and NETs. Citryll was founded by ModiQuest B.V., originator of the tACPA patents, Helmuth van Es, CEO Citryll (co-founder of Audion Therapeutics, Galapagos, Antabio and Effecta Pharma), and Renato Chirivi, CSO Citryll and co-inventor of tACPA antibodies.

At Crossfire Oncology we have a deep understanding of kinases that play a pivotal role in many cellular processes, including proliferation, survival, migration, and differentiation.

Based on our proprietary EPriL (Energetically Privileged Ligands) chemistry we have developed a unique platform of kinase inhibitors, degraders, and degrader antibody conjugates (DACs). This allows us to select and develop the most suitable approach for each target kinase to ensure an optimal therapeutic effect.

 

The Crossfire team has decades of experience in medicinal chemistry and was closely involved in the design of clinically and commercially successful drugs. BAL0891, a potent TTK/PLK1 inhibitor, was fully designed in house and is currently in clinical development.

CVIS specialises in designing, building, supporting and managing IT4R & D solutions. Our package includes HPC clusters and cloud solutions, managed services, network management and maintenance and security. We focus primarily, but not exclusively, on the pharmaceuticals, life sciences and manufacturing industry in the SME sector. Regardless of which sector you are active in, R&D is vital for your core business. Pure computing power, capable of being deployed flexibly and so ensuring that your Intelligent Property is kept secure , is a key element. Integration with your office automation or business processes often plays a part, too. CVIS has many years of experience in this area of complex IT infrastructures for R&D. We guide the customer from A to Z and each project is delivered as a turnkey solution.

Derks & Derks has been an HR specialist in life sciences for over 20 years. This sector is more dynamic than ever, with innovation advancing at a rapid pace, creating real value for patients and clients in sub-sectors such as pharma, medical devices, biotech and food. While technology, research and digitisation have an indispensable influence, human talent remains the central success factor. Derks & Derks offers a ‘full package’ service of Recruitment & Development Solutions, to make the best possible contribution to the success of your team. You can also contact us for specific HR issues within each phase of your biotech company, from start-up / scale-up to commercial production. We offer tailormade HR solutions for every organisation.

De Vries & Metman is a leading patent office in the Netherlands. Protecting innovation is our passion. We help clients to valorise their inventions and realize their commercial ambitions. We assist clients in all patent matters – regardless of complexity or technical area – on the basis of clear advice that is tailored to the business.

Dotcombusiness focuses on total solutions in which the human factor is central. As a knowledge provider in the field of office automation, we provide mid-size and and small businesses with the whole range of services, from consulting, security and monitoring to the introduction of a completely new network.

Eurofins Spinnovation Analytical is a contract research organisation specialised in delivering high-end analytical services to the life sciences industry. Our core activity focuses on addressing your needs in process and drug development, product characterisation, manufacturing process optimisation and troubleshooting, QC/QA testing, and batch release of your API and biologics.

While technology has changed the world all around us, in the lab, surprisingly few things have changed regarding how science is performed. With our cell culture automation platform, our mission is to reinvent the lab.

Genase Therapeutics is developing a small molecule inhibitor against a metabolic target with therapeutic potential in hematologic malignancies and potentially solid tumors.

GlycoMScan provides contract research and analytical services for pharma, life sciences companies and academia. We are specialised in mass spectrometry and have a background in protein and glycosylation analyses, and especially in the building blocks of these, which are present in the intracellular metabolism. The company started in April 2018, performing preclinical analyses of nucleotide sugars for a start-up pharmaceutical company in San Francisco that is aiming to develop the first medicine for PMM2-CDG, a rare congenital disorder of glycosylation. Very quickly, the number of customers grew from 1 to >10.

Glycostem is a life science company that is opening new horizons in allogeneic NK-cell-based immunotherapy, thanks in large part to our cutting-edge platform technology. In recent years, Glycostem has enabled a closed-system cell-culture process for the large-scale expansion of CD34+ hematopoietic stem and progenitor cells, derived mainly from umbilical cord blood.

There has been a revolution in cancer treatment, whereby the immune system is leveraged by new precision medicines. However, for the majority of cancer patients these therapies fail to provide durable clinical benefit. This is where Immagene aims to make a difference.

ImmunoPrecise is a full-service, therapeutic antibody discovery company focused on the next generation of antibody discovery. We aim to deliver the most therapeutically-relevant antibodies, in a shorter period of time, with the highest probability of succeeding to clinical trials.

InProcess-LSP provides Process Analytical Services to the life sciences and pharma industries. We offer all services, from consultancy and feasibility up to full application development, validation and implementation.

Lead Pharma is a biopharmaceutical company focusing on the discovery and development of innovative medicines for the treatment of autoimmune diseases and cancer. Lead Pharma’s drug discovery engine combines medicinal, structural and computational chemistry with molecular pharmacology, cell and tissue-based pharmacology. Through this, the company aims to identify first and/ or best-in-class small molecule drugs.

LiteVax BV, founded in 2012, focuses on the development of novel, synthetic adjuvants for a wide range of innovative prophylactic and therapeutic vaccines. These adjuvants not only increase the efficacy of vaccines, but also lower the dose of vaccine and number of injections needed. Our research activities are at the interface between organic chemistry and immunology, with a strong emphasis on structure-activity relationships.

Our mission is to develop the next generation of (nano)medicines: low in side-effects and high in efficacy. Our nanoparticle platform promises exactly this. It uses organ or cell-targeting to prevent side-effects, and mRNA, the software of the body, to treat diseases with unprecedented efficacy. We are developing an mRNA-centred platform and are currently working on a first drug. This is intended to both prove the worth of the platform and provide a valuable drug for patients with Chronic Kidney Disease.

MSD Animal Health, known as Merck Animal Health in the United States and Canada, is the global animal health business unit of MSD. MSD Animal Health offers veterinarians, farmers, pet owners and governments the widest range of veterinary pharmaceuticals, vaccines and health management solutions and services. We are dedicated to preserving and improving the health, well-being and performance of animals.

A startup biotech company specialised in sustainable nanotechnology.

Nelisca is a nationally operating accountancy and consultancy firm for small and medium-sized enterprises – from startups to scale-ups – in the life science sector. Our specialists offer a relevant range of products when it comes to services in the field of accountancy, administration, tax or legal matters, recruiting qualified personnel, or subsidies.

Oncolines is a precision medicine services company in oncology and cancer immunotherapy. Our clients are clinical and preclinical biopharma companies and academic institutions that seek differentiation for their drugs and drug candidates. Using cancer cell panel profiling, we identify predictive drug response biomarkers, new disease indications and synergistic drug combinations. We present results in a unique interactive reporting format to facilitate the easier and faster interpretation of results. We perform gene and protein expression analysis, DNA and RNA sequencing to investigate the mechanism of action of compounds. We generate, process, analyse, visualise and interpret complex data. We present meaningful data and discuss them with our clients. With our extensive reference compound database, we identify differentiation and mechanism of action. We share our knowledge in cancer drug development. We help cancer researchers to move their projects to the clinic faster.

Our three pillars — women’s health, biosimilars and established medicines — are the foundation for how we strive to achieve our vision to create a better and healthier every day. We work to provide medicines and other products that help address a wide array of conditions and diseases that women and their loved ones face. Our hope is to give people more choice throughout their lives.

Osteo-Pharma is a life sciences company focused on the development of novel pharmaceuticals and medical devices to promote the local healing of bone fractures or defects.

Pedersen & Partners is a leading international Executive Search firm, established in 2001. Their values Trust, Relationship and Professionalism apply to their interaction with clients as well as executives.

Their integrated, international global approach to Executive Search is tailored to meet the current and future requirements of the Life Sciences & Healthcare industries. The international team of expert search consultants combine in-depth understanding of the industry and its trends. Extensive experience within the sector helps to offer industry insights and sensible input when supporting clients in finding leadership talents, locally and across borders.

As one of the most experienced and complete providers of laboratory services worldwide, OneSource is positioned to offer a valuable, customisable and profitable partnership.

Together, we can achieve Quality as our specialists collaborate to achieve the best result. We are curious and driven: always looking for ground-breaking IT technology that will reshape the world of Quality. PharmSupport grew out of an ambition to provide a contemporary perspective on Quality within organisations. We combine decades of experience in a decisive organisation that upholds a result-oriented way of working. Modern IT technology plays an important role for us as it shapes processes, organisations and how we work together.

PimBio B.V. was founded in 2014 to develop new and promising microfluidic devices for the bioengineering of physiologically relevant living tissue which can be used in scientific research, regenerative medicine and industry.

Pivot Park is a life sciences campus with a special focus on pharmaceutical innovation. The campus offers lab and office space of any size with access to high-quality pharmaceutical R&D facilities and infrastructure and expertise. This gives companies the opportunity to accelerate, grow and excel in the area of ​​drug discovery and development.

Are you searching for services in assay development, High-Throughput Screening to find lead candidates for your target? Do you want your early drug discovery program to be more efficient, accurate and reproducible? The Pivot Park Screening Centre is equipped with advanced robotic systems and offers ultra-High-Throughput Screening (uHTS) and lab automation services to accelerate your drug discovery programmes.

Current pharmacokinetic profiling uses drug concentrations up to organ or total cellular levels. This does unfortunately not provide information about the actual drug concentration at the molecular target, which is expected to contribute to incorrect prediction of a drugs efficacy and safety. Consequently, subcellular drug concentrations provide the next step in pharmacokinetic profiling. QTM BioSciences is your all-in-one service partner to quantify and predict subcellular distribution of your drug candidate or delivery platform. Moreover, we determine the role of organelles membrane transporters in the subcellar distribution.  

Rescop provides a complete portfolio of consultancy services and software products that enable businesses to achieve GxP compliance for all of their processes and resources, ranging from facilities and utilities to equipment and IT. This integrated approach allows Rescop to offer end-to-end compliance solutions that ensure regulatory compliance across the entire organization.

We aim to enable the next medical revolution by providing researchers with high-performance RNA products. We believe that mRNA is the tool to accelerate research, revolutionise vaccine development and create breakthrough therapies. We believe that all the motivation and disease/drug-development knowledge needed to change the world is already out there, in the heads of doctors, pharmacists and life-science researchers. All that is needed now is access to high-quality mRNA and the expertise to use it effectively. It is our mission to give you that access, to be your partner for life-changing discoveries and medicines. It’s a mission that drives us, motivates us and is the reason why we began RiboPro.

SPIE, de onafhankelijke Europese leider in multitechnische diensten op het gebied van energie en communicatie, is exclusieve onderhandelingen aangegaan met Strukton over de overname van Worksphere, de specialist in slimme en duurzame gebouwdiensten in Nederland, met een toonaangevende expertise in datagedreven energie-efficiëntieoplossingen. De overname biedt een nieuwe stimulans in het terugdringen van de CO₂-uitstoot en om versneld de kwaliteit van de gebouwde omgeving te verbeteren.

SUBLIN, a spinout from the pharma branch of NanoSERVE, aims to develop an oral insulin formulation that will provide diabetic patients with a disruptive alternative to cumbersome insulin injections.

Synaffix is a biotechnology company that enables highly competitive, targeted cancer therapeutics using our site-specific antibody-drug conjugate (ADC) technology platform. The platform consistently delivers more effective and better-tolerated ADCs compared to all three major clinical-stage technologies.

Thema Group is a life sciences recruitment agency for Europe-based domestic and international businesses with offices in the Netherlands, Belgium and Germany. Thema Group primarily focuses on finding candidates for the pharmaceutical industry and biotechnology, plus work involving laboratory technology, medical devices, process technology and chemistry and food B2B.  Thema Group matches the specific needs of companies to the personal ambitions and wishes of candidates, providing personnel solutions that are successful for both life science companies and candidates.

At Trained Therapeutix Discovery we employ advanced bioengineering methods to produce nanobiologic therapeutics. Nanobiologics are therapeutic materials constructed from molecular building blocks that our body produces naturally.

The advantage of this approach is that we ‘hijack’ natural mechanisms to engage the immune system with materials that are inherently well tolerated by the body, allowing us to take control of the immune response by regulating trained immunity. The Trained Therapeutix Discovery nanobiologic platform technology is fully modular, flexible, and can be judiciously finetuned.

With some 40 lawyers, we are one of the largest independent legal offices in the southern Netherlands. We have a solid reputation in the Netherlands and internationally. For more than 60 years, we have advised companies and supported entrepreneurs in their growth, while also standing by them in challenging times. With specialists in 10 disciplines and expertise in different sectors, we are your ideal partner.

Growing your life science business – turning your creativity and invention into a commercial success – can feel like guiding a car down a bumpy road. Logical, because designing and building a production facility is not your core business. But it is ours. VILS helps you in taking your crucial next step by developing a suitable concept and lean design package that supports the swift design & build execution of your project.

10 years ago, Pivot Park opened its doors to the world. Thanks to your commitment, support and confidence, we have been able to grow it into the successful and innovative biopharmaceutical campus it is today.